What is an IV Persantine-Thallium Stress Test?

• This test ia an alternative procedure for patients with coronary artery disease who can not exercise on a treadmill.
• An IV line is started to administer the persantine and the thallium.
• Persantine helps to expand the coronary arteries increasing the blood flow to the area. This effect is similar to what happens during vigorous exercise.
• Thallium (a radioactive isotope) is detected by X-rays and shows which parts of the heart muscle are receiving enough oxygen.
• Side effects of thallium are rare and may include rashes or low blood pressure.
• Possible temporary side effects of Persantine may include: headache, dizziness, nausea/vomiting, chest discomfort.
• Electrodes will be placed on the chest so that the heart rate and rhythm will be monitored by an electrocardiogram (EKG).
• A special camera takes pictures of the heart.
• This test is usually administered in 2 phases with each phase lasting 30-60 minutes. The patient may be required to return the following day to complete the second phase.
• The phase of this test takes about 60 minutes.
• This test must be ordered by the doctor.

Why is a Persantine Stress Done?

• This test will help the doctor to evaluate the patient's cardiac condition related to:
  • Irregular heart rhythms
  • Which areas of the heart are not getting enough blood and oxygen.
  • How quickly the heart recovers after exercise.

What Preparation is Needed?

• Nothing to eat or drink for 3 hours prior to the test.
• Do not smoke or drink caffeine for at least 6 hours prior to the test.
• It is important for the patient to ask his doctor:
  • how to adjust his insulin and food intake prior to the test if he is a diabetic
  • if he should take his regular medications the morning of the test.
  • if he is on a Beta Blocker, can he STOP taking this medication 72 hours before the test as this is recommended for best results
• If the patient is taking aminophylline or theodur, he must discontinue it for 48-72 hours prior to the test.
• The patient must notify his physician if:
  • he is allergic to Theophylline or Persantine
  • he has asthma, chronic lung disease or any heart conditions
• Do not apply lotions, oils or powders to the chest area.